D-penicillamine resistant T cells in patients with chronic articular rheumatism.

Evaluation of Regulatory T Cells in Patients with Acute and Chronic Brucellosis

Background:   Brucellosis is one of the most common chronic diseases, with widespread distribution. In spite of cell-mediated immunity (CMI) modulated mainly via activated T-helper type 1 (Th1) cells, brucellosis can advance to chronic disease in about 10-30% of cases. Regulatory T cells (Treg cells) are involved the immune response to brucellosis; however, their role, particularly in...

Psychosomatic non-articular rheumatism.

It seems now to be fairly widely agreed that emotional factors are relevant to the study of rheumatism, and particularly of non-articular rheumatism or fibrositis. The Horder Report (1941) stated that " Worry, anxiety, mental shock, can be often recognized as promotive of rheumatic disease ". The relationship is perhaps more often expressed as a matter of differential diagnosis between muscular...

Non-Articular Rheumatism (Fibrositis)

Thrombokinetics in patients with rheumatoid arthritis treated with D-penicillamine.

The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 with a normal platelet count and 9 with thrombocytopenia (platelet count 50-130 X 10(9)/1). Age matched control patients not treated with D-peni...

Chronic inorganic mercury poisoning treated with N-acetyl-D-penicillamine.

Gledhill, R. F., and Hopkins, A. P. (1972). Brit. J. industr. Med., 29, 225-228. Chronic inorganic mercury poisoning treated with N-acetyl-D-penicillamine. The case history is presented of a man intoxicated by mercury during his employment as a filler of thermometers. The mean daily urinary excretion of mercury was 661 ,ug for five estimations before treatment. The mean excretion was 875 ,ug fo...